产品货号：
Z12448
中文名称：
CAMKK2抗体
英文名称：
Anti-CAMKK2 antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CAMKK2 antibody |
| 指标别名 | CaM kinase kinase 2;CaM kinase kinase beta;CaM KK 2;CaM KK beta;CAMKK;CaMKK 2;CaMKK beta;CAMKK2;CAMKKB;KIAA0787 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,ICC/IF,ELISA |
| 基因名称 | CAMKK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CAMKK2 recombinant protein (Position:M1-G349). |
| 实际分子量 | 60KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CAMKK2,Calcium/calmodulin-dependent protein kinase kinase 2,is an enzyme that in humans is encoded by the CAMKK2 gene.The product of this gene belongs to the serine/threonine-specific protein kinase family,and to the Ca++/calmodulin-dependent protein kinase subfamily.This protein plays a role in the calcium/calmodulin-dependent(CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4.CaMKK2 regulates production of the appetite stimulating hormone neuropeptide Y and functions as an AMPK kinase in the hypothalamus.It also has an important role in the development of hyperalgesia and tolerance to opioid analgesic drugs,through reduction in downstream signalling pathways and mu opioid receptor downregulation.Inhibition of CaMKK2 in mice reduces appetite and promotes weight loss. |
| Uniprot ID | Q96RR4 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | calcium/calmodulin-dependent protein kinase kinase 2,beta |
| 蛋白名全称 | Calcium/calmodulin-dependent protein kinase kinase 2(CaM-KK 2/CaM-kinase kinase 2/CaMKK 2) |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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